Treatment-resistant depression
Adults with treatment-resistant depression (TRD), meaning depression that has not adequately responded to previous antidepressant treatment.
REMS-certified SPRAVATO® treatment center · Now accepting new patients in Phoenix
If two or more antidepressants have not provided enough relief, our team can evaluate whether supervised SPRAVATO® treatment may be appropriate.
Phoenix, AZ · Insurance benefits verified before treatment.
REMS-certified
Protocol-driven monitoring
FDA-approved
For treatment-resistant depression
Insurance handled
We file the authorization
Board-certified
15+ years in practice
Patient experiences
Patient experiences vary. Testimonials reflect individual experiences and are not a guarantee of outcome.
Do I qualify?
SPRAVATO® is FDA-approved for adults with treatment-resistant depression (TRD), a form of depression that has not adequately responded to previous antidepressant treatment.
Adults with treatment-resistant depression (TRD), meaning depression that has not adequately responded to previous antidepressant treatment.
Treatment history is reviewed as part of determining whether SPRAVATO® may be appropriate. Insurance authorization requirements vary by plan.
Your diagnosis, treatment history, current medications and overall health are reviewed to determine whether SPRAVATO® may be appropriate for you.
Not sure whether you meet the criteria? That is exactly what the first call is for.
Check My EligibilitySPRAVATO® is esketamine nasal spray, given under clinical supervision. Its mechanism differs from many traditional antidepressants.
Your team reviews previous treatments and whether SPRAVATO® is appropriate.
Treatment takes place in our clinic, with at least two hours of monitoring.
Arrange transportation home. Do not drive until the next day after a full night’s sleep.
If you are looking for non-medication alternatives for treatment-resistant depression, we also offer FDA-cleared TMS Therapy and Electroconvulsive Therapy (ECT). For comprehensive psychiatric care, our Medication Management providers can help evaluate your history to determine the best path forward.
Your treatment
A full psychiatric evaluation — history, every medication tried, medical factors and a baseline depression score. Also where we screen for what rules SPRAVATO® out.
Authorization timing varies by insurance plan. Our team submits the required documentation and works directly with your insurer throughout the process. If authorization is denied, we can review available next steps, including an appeal when appropriate.
Treatment is typically given twice weekly during the initial four-week induction phase. Your prescribed medication regimen will depend on your diagnosis and individualized treatment plan. Your clinical team will monitor your symptoms and response throughout treatment. Individual response and timing vary.
Once you are responding, sessions taper to a maintenance schedule set by how you are actually doing — tracked at every visit.
You self-administer
The nasal spray, under the direct supervision of our trained staff.
At least two hours of monitoring
In a private room with a recliner. Vital signs checked throughout; most side effects resolve inside this window.
Arrange a ride home
No driving or operating machinery until the next day, after a full night’s sleep.
2929 E Camelback Rd #119, Phoenix, AZ 85016
Or call (602) 824-8404 — Monday to Friday, 8am–5pm.
Insurance
Many commercial insurance plans, Medicare and some Medicaid plans may provide coverage for SPRAVATO®, subject to eligibility, plan requirements and prior authorization.
Swipe to see all 17 plans →
Approval typically takes three days to two weeks. We handle the paperwork and talk to your insurer directly, so the wait is on us rather than on you.
We confirm what your policy covers — the medication and the observation visit are billed separately — before anything begins. Manufacturer savings programs may apply; we will check.
Coverage may be available through Medicare and certain AHCCCS plans for eligible patients. Coverage requirements and prior authorization vary by plan. Our team will verify your benefits before treatment.
Denied before, or worried you will be? If coverage is denied, our team will review the reason and discuss available next steps, including an appeal when appropriate.
Verify My CoverageSafety
SPRAVATO® can cause sedation, dissociation, respiratory depression and increases in blood pressure, and it carries a risk of abuse and misuse. Because of these risks, it is available only through the SPRAVATO® REMS program and requires monitoring by a healthcare provider after administration.
Direct supervision
A clinician is with you while you self-administer.
Two-hour monitoring
After every dose, with vital signs observed.
Transportation required
No driving until the next day, after a full night’s rest.
These usually begin shortly after the dose and resolve the same day — which is exactly what the monitoring period is for.
Your evaluation screens for all of these before anything is prescribed.
SPRAVATO® is not a pain reliever or an anesthetic, and it is never taken home. Tell your medication management provider about every condition and medication you are on — that is how we judge whether it is safe for you specifically. This page is general information, not medical advice, and not a substitute for the full Prescribing Information and Medication Guide your clinician will review with you.
Patient experiences
Reviews are reproduced as published by their authors on Google and describe care at this practice generally, not SPRAVATO® treatment specifically. Individual results vary.
Questions
For most patients, yes. The majority of commercial plans, Medicare and many Medicaid programs — including Arizona’s AHCCCS — cover SPRAVATO® for treatment-resistant depression. Coverage is not automatic: insurers require a prior authorization first. Our care coordinators handle that paperwork and talk to your insurer directly.
Your out-of-pocket cost depends on your insurance plan and may include a deductible, copay or coinsurance for the medication and treatment-related services. Before treatment begins, our team will verify your benefits and review your expected patient responsibility with you. Eligible patients with commercial insurance may also qualify for manufacturer savings or rebate programs that can help with certain SPRAVATO® medication and treatment-observation costs. Our team can help you determine whether you may be eligible.
You self-administer SPRAVATO® nasal spray under the supervision of a healthcare provider at our REMS-certified treatment center. After administration, you will be monitored for at least two hours. Your healthcare provider will monitor you for potential side effects and determine when you are clinically stable and ready to leave. You will need to arrange transportation home and should not drive or operate machinery until the next day, after a full night’s sleep.
Response to SPRAVATO® varies. Some patients may experience improvement earlier in treatment, while others may require multiple treatment sessions before noticing a change. Your clinical team will monitor your symptoms throughout treatment and evaluate your individual response.
No. You will need to arrange transportation home after each SPRAVATO® treatment. You should not drive or operate machinery until the next day, after a full night’s sleep. Your healthcare provider will determine when you are clinically stable and ready to leave the treatment center.
Dissociation, dizziness, fatigue, nausea or vomiting, a feeling of being drunk or euphoric, anxiety or numbness, and a spinning sensation. They usually begin shortly after the dose and resolve the same day, which is what the monitoring period is for.
Prior authorization usually takes three days to two weeks. Denials do happen, most often because of missing documentation — if that happens, our team files the appeal on your behalf with the additional clinical evidence.
No referral is required to schedule an appointment with Interventional Psychiatry of Arizona. However, referral or authorization requirements may vary depending on your insurance plan and the services you receive. Our team can verify your benefits and any applicable requirements before your appointment.
Get started
Prior authorization takes three days to two weeks. The sooner we start it, the sooner you can start treatment — and the first conversation costs you nothing.
In crisis? Call 911, or call or text 988 for the 24/7 Suicide & Crisis Lifeline.
Mon–Fri
8am–5pm